Tuesday's loss takes United to within one of their record of 14 Premier League defeats in the 2023-24 season, leaving them languishing down in 13th in the table as Amorim struggles to instigate any real change.
The 30-year-old Portuguese star has been linked in recent days with a £90 million (107.4 million euros) switch to Spanish giants Real.
United, who travel to face high-flying Nottingham Forest on Tuesday, are a lowly 13th in the Premier League, 12 points off the top four with just nine games to go.
Thomas Tuchel has insisted Harry Maguire will "always be in contention" for England despite overlooking the Manchester United defender for his first two games in charge.
Real Sociedad's Mikel Oyarzabal coolly netted a penalty to hold Manchester United to a 1-1 draw in a Europa League last 16 first leg clash on Thursday.
Manchester United's dismal season hit a new low as the FA Cup holders crashed out after a 4-3 penalty shoot-out defeat against Fulham in the fifth round on Sunday.
Manchester United boss Ruben Amorim described his side as "soft" despite fighting back from 2-0 down to salvage a 2-2 draw at Everton on Saturday.
Bruno Fernandes inspired a Manchester United rally from two goals down to avoid another damaging defeat for Ruben Amorim in a 2-2 draw at Everton on Saturday.
The 22-year-old has been one of the few bright points in a campaign to forget at Old Trafford.
Ruben Amorim says he and his Manchester United players are "fighting" for their jobs in the final months of the season after a chastening campaign so far.
United's third-placed finish in the Europa League first phase ensured they avoided a two-legged playoff to reach the last 16.
Manchester United manager Ruben Amorim believes the club's 63-year-old goalkeeper coach has a better chance of making his team than outcast striker Marcus Rashford.
Lisandro Martinez's deflected winner offered some respite to Amorim, who has won just four of his 12 Premier League games in charge.
Ruben Amorim might not have been historically accurate when he labelled his Manchester United flops as "maybe the worst team" in the club's history, but his astonishing claim did expose the extent of the problems facing the beleaguered boss.
United crumbled to a sixth loss in 11 Premier League games since Amorim arrived from Sporting Lisbon to replace the sacked Erik ten Hag.
Manchester United manager Ruben Amorim urged the leaders in the Premier League club's squad to step up and help players who are "too afraid" to perform on the pitch amid a run of poor results.
Ruben Amorim says Manchester United are "starving for leaders" during a turbulent period ahead of a daunting trip to runaway Premier League leaders Liverpool on Sunday.
Just two months into his tenure, Amorim conceded this week that his job is on the line unless results begin to improve.
Thursday's 2-0 loss at Molineux -- United's third consecutive defeat -- made Amorim the first United manager to lose five or more of his first 10 matches in charge since Walter Crickmer in January 1932.
