Israel braced for more protests yesterday after clashes at Jerusalem's flashpoint Al-Aqsa Mosque compound wounded more than 200 people and as the US, EU and regional powers urged calm after days of escalating violence.   

In the unrest following Muslim prayers on Friday, Israeli riot police fired rubber bullets, tear gas and stun grenades at Palestinians who hurled rocks and fireworks at Islam's third-holiest site which is also revered by Jews.

Israeli police said 17 officers were wounded while the Palestinian Red Crescent reported that 205 Palestinians were injured in the violence at Al-Aqsa and across annexed east Jerusalem.

Video footage showed Israeli forces storming the mosque's sprawling plaza and firing sound grenades inside the building, where throngs of worshippers including women and children were praying on the last Friday of the Muslim holy month of Ramadan.

The clashes came after tensions soared in recent weeks, over Israeli restrictions on access to parts of the Old City during Ramadan and the threat of evicton hanging over four Palestinian families in east Jerusalem to make way for Jewish settlers.

The United States said it was "extremely concerned" by the events and urged both sides to "avoid steps that exacerbate tensions or take us farther away from peace".

"This includes evictions in east Jerusalem, settlement activity, home demolitions and acts of terrorism," the State Department said.

The European Union called on the authorities "to act urgently to de-escalate the current tensions in Jerusalem," saying "violence and incitement are unacceptable and the perpetrators on all sides must be held accountable".

Jordan condemned Israel's "barbaric attack" in Jerusalem, calling on the international community to stop the "escalation and violations" at Al-Aqsa Mosque.

Saudi Arabia, UAE, Egypt, Turkey, Qatar and Bahrain also blasted Israeli forces for the confrontation.

Iran called on the United Nations to condemn the Israeli police actions, arguing that "this war crime once again proved to the world the criminal nature of the illegitimate Zionist regime".

The Al-Aqsa mosque compund has an explosive history. In 2000, the second Palestinian intifada broke out after then Israeli opposition leader Ariel Sharon made a high-profile visit that Palestinians viewed as an intolerable provocation.